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Publications
Ben-Azu Benneth, Adebayo OG, Fokoua AR, Onuelu JE, Asiwe JN, Moke EG, Omogbiya AI, Okpara OL, Okoro JE, Oghenevwerutevwe OM, Uruaka CI. Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice. Brain Disorders, 13; 100122, https://doi.org/10.1016/j.dscb.2024.100122, 2024
Ben‑Azu Benneth, Moke EG, Chris‑Ozoko LE, Jaiyeoba‑Ojigho EJ, Adebayo OG, Ajayi AM, Oyovwi MO, Odjugo G, Omozojie VI, Ejomafuwe G, Onike N, Eneni AO, Ichipi‑Ifukor CP, Achuba IF. Diosgenin alleviates alcohol‑mediated escalation of social defeat stress and the neurobiological sequalae. Psychopharmacology https://doi.org/10.1007/s00213-023-06509-1, 2024
Okhue E, Kadiri HE, Ichipi‐Ifukor PC, Ben‐Azu Benneth, Asagba SO, Achuba FI, Oyem JC. Prenatal double‐hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido‐nitrergic stress and endocrine perturbations Biometalshttps://doi.org/10.1007/s10534-023-00563-0, 2024
Ben-Azu Benneth, Adebayo OG, Fokoua AR, Oritsemuelebi B, Chidebe EO, Nwogueze CB, Kumanwee L, Uyere GE, Emuakpeje MT. Antipsychotic effect of diosgenin in ketamine-induced murine model of schizophrenia: Involvement of oxidative stress and cholinergic transmission. IBRO Neuroscience Reports 16, 86–97, https://doi.org/10.1016/j.ibneur.2023.12.008, 2024
Onyekweli CC, Ben-Azu Benneth, Oyovwi OM, Nwangwa EK, Ovuakporaye IS, Moke GE, Agbonifo-Chijiokwu E, Onome BO, Emojevwe V, Rotu AR. Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and neurochemical changes in rats. Food and Chemical Toxicology 184, 114340, https://pubmed.ncbi.nlm.nih.gov/38097001, 2024
Ben-Azu Benneth, Adebayo G. Olusegun, Moke G. Emuesiri, Omogbiya I. Adrian, Oritsemuelebi Benjamin, Chidebe O. Emmanuel, Umukoro Emuesiri, Nwangwa K. Eze, Etijoro Emmanuel, Umukoro Emmanuel, Mamudu J. Elizabeth J, Chukwuma Chineye. Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder. Journal of Psychiatric Research 168, 165–175, https://doi.org/10.1016/j.jpsychires.2023.10.057, 2023
Graham AS, Ben-Azu Benneth, Tremblay ME, Torre III P, Senekal M, Laughton B, Kouwe A, Jankiewicz M, Kaba M, Holmes MJ. A review of the auditory-gut-brain axis. Frontiers in Neuroscience, DOI 10.3389/fnins.2023.1183694, https://doi.org/10.3389/fnins.2023.1183694, 2023
Ben-Azu Benneth, del Re EC, VanderZwaag J, Carrier M, Keshavan M, Khakpour M, Tremblay M. Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia. Front. Cell. Neurosci., 17, https://doi.org/10.3389/fncel.2023.1139357, 2023
Adebayo AG, Otene CI, Emmanuel MO, Onwuka FC, Aduema W, Ben-Azu Benneth, Nwikue G, Asiwe JN, Ike AO, Wopara I, Omeiza NO, Abeje JI, Onasanwo SA. Chronic intermittent oxygen deprivation alters hippocampal cholinergic and glutamatergic system via oxido-inflammatory burden and HIF-1a/Bcl-2 activity in hypothyroid mice: Ameliorative role of Ginkgo biloba supplement. Phytomedicine Plus 3, 100451, https://doi.org/10.1016/j.phyplu.2023.100451, 2023
VanderZwaag J, Halvorson T, Dolhan K, Šimončičová E, Ben-Azu Benneth, Tremblay M. The Missing Piece? A Case for Microglia’s Prominent Role in the Therapeutic Action of Anesthetics, Ketamine, and Psychedelics. Neurochemical Research, https://doi.org/10.1007/s11064-022-03772-0, 2022
Khakpour M, Ibanez FG, Bordeleau M, Picard K, Mckee-Reid L, Ben-Azu Benneth, Maggi L, Tremblay M. Manual versus automatic analysis of microglial density and distribution: a comparison in the hippocampus of healthy and lipopolysaccharide-challenged mature male mice. Micron 161, 103334, https://doi.org/10.1016/j.micron.2022.103334, 2022